Abstract The formation, development, and current status of a major instructional materials preparation project, the CAIDENT Project, at the School of Dentistry, The University of Michigan, is discussed. A rationale for the place of individualized instruction in general and CAI in particular is presented. Topics include staffing strategies and ways to encourage faculty participation. Examples are included to illustrate operational CAI programs at Michigan in Pedodontics and Oral Diagnosis. Comments about the future of CAI in the Health Sciences are included.