EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ELECTROLYTES (CALCIUM, POTASSIUM, SODIUM AND CHLORIDE) ON BRAIN AND HEART IN HIGH SUCROSE DIET FED RATS

ABSTRACT

Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Electrolytes status were analysed in the plasma, liver and heart after four weeks of feeding.   Feeding of rats with high sucrose diet revealed a significant (p<0.05) increase in chloride, potassium and calcium in heart and significant (p<0.05) increased sodium level while potassium and chloride were significant (p<0.05) decreased in brain . Thus, vegetables extracts modified diet may be a good approached to improved electrolyte imbalance induced by excess sugar intake.

TABLE OF CONTENTS

CHAPTER ONE

1.0     Introduction

CHAPTER TWO

2.0     Malnutrition and Cardiovascular diseases

2.1     Vegetable plants

2.1.1  Vernonia amygdalina (Efo ewuro)

2.1.2  Telferia occidentalis (Ugwu)

2.2     Sodium Ion

2.4     Potassium Ion

2.5     Chloride Ion

2.6     Calcium Ion

CHAPTER THREE

3.0     Materials and Methods

3.1     Apparatus and Equipments

3.2     Chemical reagents

3.3     Collection and extraction of plant materials

3.3.1  Telferia occidentalis      

3.3.2  Vernonia amygdalina

3.4     Methods

3.4.1  Diet composition

3.4.2  Feeding and grouping of animals

3.4.3  Animal Sacrifice

3.5     Organ Homogenization

3.6     Biochemical analysis

3.7     Statistical Analysis

CHAPTER FOUR

4.0     Results

CHAPTER FIVE

5.0     Discussion, Conclusion and Recommendation

5.1     Discussion

5.2     Conclusion

5.3     Recommendation

          References

Appendix